4-fluoro-2-methylbenzene-1-sulfonyl chloride

4-fluoro-2-methylbenzene-1-sulfonyl chloride - Names and Identifiers

Name	4-Fluoro-2-methylbenzenesulphonyl chloride
Synonyms	2-(Chlorosulphonyl)-5-fluorotoluene 4-fluoro-o-toluenesulfonyl chloride 4-Fluoro-o-toluenesulphonyl chloride 4-fluoro-2-methylbenzenesulfonyl chloride 4-FLUORO-2-METHYLBENZENESULFONYL CHLORIDE 4-FLUORO-2-METHYLBENZENESULPHONYL CHLORIDE 4-Fluoro-2-methylbenzenesulphonyl chloride Benzenesulfonyl chloride, 4-fluoro-2-methyl- 4-fluoro-2-methylbenzene-1-sulfonyl chloride
CAS	7079-48-3
EINECS	627-540-5
InChI	InChI=1/C7H6ClFO2S/c1-5-4-6(9)2-3-7(5)12(8,10)11/h2-4H,1H3

4-fluoro-2-methylbenzene-1-sulfonyl chloride - Physico-chemical Properties

Molecular Formula	C7H6ClFO2S
Molar Mass	208.64
Density	1.433g/mLat 25°C(lit.)
Boling Point	245-246°C(lit.)
Flash Point	>230°F
Vapor Presure	0.00539mmHg at 25°C
Appearance	Liquid
Color	Colorless to yellow
BRN	6720115
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.5370
MDL	MFCD03094390

4-fluoro-2-methylbenzene-1-sulfonyl chloride - Risk and Safety

Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 3265 8/PG 2
WGK Germany	3
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

4-fluoro-2-methylbenzene-1-sulfonyl chloride - Introduction

chloride is an organic compound with the chemical formula of C7H6ClFO2S, which is a derivative of benzenesulfonyl chloride. The following is a description of its nature, use, preparation and safety information:

Nature:
-chloride is a colorless to light yellow liquid with a pungent odor.
-It has a density of 1.44g/cm³, a melting point of -29°C, and a boiling point of 144-146°C.
-It is insoluble in water and soluble in organic solvents such as ether and dichloromethane.

Use:
-chloride is a commonly used reagent in organic synthesis, which can be used to introduce 4-fluoro and sulfonyl chloride functional groups.
-It is often used as an intermediate for the synthesis of biologically active compounds, such as drugs and pesticides.

Preparation Method:
-chloride can be prepared by reacting 4-fluoro-2-methylbenzenesulfonic acid with phosphorus oxychloride.
-The reaction conditions are generally carried out at room temperature, and the product is extracted and purified.

Safety Information:
-chloride is a harsh chemical. Wear appropriate protective gloves and glasses when using it to ensure good ventilation.
-avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water, and medical treatment.
-It is a flammable liquid, avoid contact with open flames and high temperature sources.
-Keep away from oxidizing agents and acids during storage and use.

Last Update：2024-04-09 02:00:47